Isonicotonic Acid Hydrazide in the Treatment of Endometrial Tuberculosis
نویسندگان
چکیده
Having read encouraging reports on the efficacy of Isonicotonic Acid Hydrazide we decided to try this drug in endometrial tuberculosis. Whereas improvement in cases reported so far is based on systemic response and radiological changes, it has not possible to examine the diseased tissues histologically. Since the endometrial tissue can be removed easily with very little discomfort to the patient, we ventured to take up the study of changes in the endometrium of these patients while under treatment with isonicotonic acid hydrazide.
منابع مشابه
Onm-18: Infertility and Pregnancy Outcome in Female Genital Tuberculosis
Background: Tuberculosis of the genital tract is one of the major causes of gynecological morbidity. Genital TB affects about 12% of patients with pulmonary tuberculosis and represents 15-20% of extrapulmonary tuberculosis. Genital TB may be asymptomatic but involves genital organs such as fallopian tubes, endometrium, ovaries, cervix, vulva/ vagina and myometrium. The major presenting symptom ...
متن کاملAcylation of hydrazides with acetic acid and formic acid.
In peptide synthesis, hydrazides are important intermediates for the azide coupling method. A hydrazide is converted to the corresponding azide in the presence of an acid and a nitrite. When acetic acid (or formic acid) is used as the acid, partial acetylation (or formylation) of the hydrazide occurs as a side reaction. Formylation of the hydrazide is much faster than acetylation. Removal of th...
متن کاملThe Treatment of Pulmonary Tuberculosis, T. B. Meningitis and T. B. Pericarditis with the Combination of Isonicotinic Acid Hydrazide and Streptomycin
Tuberculosis is one of the commonest invalidating diseases in this country. With the advent of the new antibiotic and chemotherapeutic remedies, the outlook is not as gloomy as .before. We have had the opportunity to study some cases treated with Unicozyde (Isonicotinic Acid Hydrazide 50 mgm. plus Vitamin C 50 mgm. per tablet) and Streptomycin with other established procedures like rest and min...
متن کاملDesign, Synthesis and Biological Evaluation of 4-Benzamidobenzoic Acid Hydrazide Derivatives as Novel Soluble Epoxide Hydrolase Inhibitors
Inhibitors of soluble epoxide hydrolase (sEH) represent one of the novel pharmaceutical approaches for treating hypertension, vascular inflammation, pain and other cardiovascular related diseases. Most of the potent sEH inhibitors reported in literature often suffer from poor solubility and bioavailability. Toward improving pharmacokinetic profile beside favorable potency, two series of 4-benza...
متن کامل